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Results: Compared with the control rats, cyclosporin A and itraconazole altered the pharmacokinetics of atorvastatin significantly. The AUC0‐t values of
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The effect of TMC114, a potent next-generation HIV protease inhibitor, with low- dose ritonavir on atorvastatin pharmacokinetics [poster #H-865].
The effect of bexarotene on atorvastatin pharmacokinetics: results from a phase I trial of bexarotene plus chemotherapy in patients with advanced non-small cell
OBJECTIVE: To determine the effect of atorvastatin on cyclosporine pharmacokinetics in liver transplant recipients. METHODS: Six stable, long-term adult liver
Atorvastatin pharmacokinetics were not altered by the coadministration of atorvastatin 80 mg and amlodipine 10 mg at steady state. Other. In clinical studies in
7.2.1 Effect of Co-administered Drugs on the Pharmacokinetics of Atorvastatin; 7.2.2 Effect of Atorvastatin on the Pharmacokinetics of
A phase I dose-escalation and pharmacokinetic study of enzastaurin and erlotinib Rodon J. The effect of bexarotene on atorvastatin pharmacokinetics: results
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Pharmacokinetics of a fixed-dose combination of atorvastatin and metformin extended release versus concurrent administration of individual
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AIMS: To investigate the effects of repeated grapefruit juice (GFJ) intake on the pharmacokinetics of atorvastatin and pravastatin in Japanese subjects.
Pharmacokinetics (PK)/Safety Study of Atorvastatin in Children With Kawasaki Disease and Coronary Artery Abnormalities. This study is not yet
Effect of food on the pharmacodynamics and pharmacokinetics of atorvastatin, an inhibitor of HMG-CoA reductase. Eur J Drug Metab Pharmacokinet.
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GSK2248761 on the pharmacokinetics of simvastatin, atorvastatin, and rosuvastatin in healthy adult subjects. Phase: I. Study Period: 14 July 2010 - 06 August
To investigate the potential effect of atorvastatin 80 mg/day on the pharmacokinetics and pharmacodynamics of the thienopyridines prasugrel
SINGLE-DOSE PHARMACOKINETICS OF COLCHICINE. THE EFFECT OF MULTIPLE DOSE ATORVASTATIN ON THE. This information is
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The pharmacokinetics of atorvastatin are complex. Based on the available published literature including the brand leader's product information, a summary of
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Effects of lamotrigine and phenytoin on the pharmacokinetics of atorvastatin in healthy volunteers. Jonathan Bullman1,; Andrew Nicholls2,
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This study compared the effects of multiple-dose administration of gemfibrozil and fenofibrate on the single-dose pharmacokinetics of atorvastatin. Gemfibrozil
We prospectively assessed atorvastatin pharmacokinetics during its continuation (in accordance with the above mentioned statin continuation protocol) in nine
Objective:To study pharmacokinetics of atorvastatin tablets in plasma of New Zealand rabbit by High efficiency liquid chromatography(HPLC) method.
Significance: Pharmacokinetics of atorvastatin were not significantly affected by coadministration with lamotrigine. Phenytoin significantly
"Coadministration of Dabigatran Etexilate and Atorvastatin: Assessment of Potential Impact on Pharmacokinetics and Pharmacodynamics.
prescription of patients with atherosclerotic heart disease mostly contains atorvastatin and clopidogrel. Aim of this study is to estimate clinical pharmacokinetic
Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin and pravastatin: results of ACTG 5108 study. J Acquir Immune Defic Syndr 2005; 39:
An open-label, crossover study of the pharmacokinetics of Insoluble Drug Delivery®-MicroParticle fenofibrate in combination with atorvastatin, simvastatin, and
No pharmacokinetic or pharmacodynamic interaction between atorvastatin and the oral direct thrombin inhibitor ximelagatran. By: Sarich TC
for the determination of atorvastatin in human plasma with UV detection and its application to pharmacokinetic studies, Arzneimittelforschung.,. 2005, 55
(2010) Lee et al. International journal of clinical pharmacology and therapeutics. OBJECTIVE: This study aimed to evaluate the effect of genetic polymorphisms
Pharmacodynamic effects and pharmacokinetics of atorvastatin after administration to normocholesterolemic subjects in the morning and
The patient recovered with supportive treatment and subsequently tolerated reintroduction of atorvastatin. Pharmacokinetic interactions can cause raised plasma
Pharmacokinetic interactions such as increased bioavailability, myositis, and rhabdomyolysis have been reported following concurrent use of atorvastatin,
Volume of distribution is found to be 5.4 and plasma protien binding is 98%. and metabolism is reported Hepatic. Renal Excretion accounts for 2% and plasma
Objectives: This study aimed to assess atorvastatin pharmacokinetic profile and variability in relation to SLCO1B1 genotype by population pharmacokinetic
Pharmacokinetics and pharmacodynamics of Atorvastatin alone and in combination with Lercanidipine in hyperlipidemic rats.
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Pharmacokinetic and bioequivalence testing of atorvastatin formulations in healthy male volunteers. Pharmazie 2006 Sep; 61(9):805-6. Mendoza L, Hajdúch M,
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tration of Atorvastatin in human plasma was necessary. This paper presents an. LC—MS method, which is suitable for use in pharmacokinetic studies.
Pharmacokinetics and Drug Metabolism. Absorption. Atorvastatin is rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to
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