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The potency and toxicity of the metabolites relative to bupropion have not been fully characterized. However, it has been demonstrated in an
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The primary significant toxicity of bupropion remains seizures, and in contrast to tricyclic antidepressants, bupropion was previously thought to have little to no
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Bupropion decreases the craving for cigarettes and symptoms of nicotine withdrawal.NICOTINE Poisoning & Drug Dependence > Poisoning/overdose
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Overdoses of up to 30 g or more of bupropion have been reported. The physician should consider contacting a poison control center for additional information
2003, Balit Corrine R, Lynch Christa N, Isbister Geoffrey Kennedy, 'Bupropion poisoning: A case series', Medical Journal of Australia, 178 61-63 (2003) [C1]
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